TargetMol

Garcinone D

Product Code:
 
TAR-TN1674
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1674-1mg1mg£201.00
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Quantity:
TAR-TN1674-1mL1 mL * 10 mM (in DMSO)£446.00
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TAR-TN1674-5mg5mg£464.00
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TAR-TN1674-10mg10mg£645.00
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TAR-TN1674-25mg25mg£946.00
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Quantity:
TAR-TN1674-50mg50mg£1,259.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 activation with IC50 values of 3.2 microM.
CAS:
107390-08-9
Formula:
C24H28O7
Molecular Weight:
428.481
Pathway:
JAK/STAT signaling; Immunology/Inflammation; NF-κb; Stem Cells; Metabolism
Purity:
0.9994
SMILES:
COc1c(O)cc2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CCC(C)(C)O
Target:
Reactive Oxygen Species; Nrf2; STAT

References

Garcinia mangostana: a source of potential anti-cancer lead compounds against CEM-SS cell line.J Asian Nat Prod Res. 2008 May-Jun;10(5-6):475-9.