TargetMol

Gentianine

Product Code:
 
TAR-TN1681
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-TN1681-1mg1mg£217.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Gentianine has anti-diabetic, antipsychotic, anti-inflammatory, hypotensive, and diuretic actions, it could be developed as a safe antihypertensive drug.
CAS:
439-89-4
Formula:
C10H9NO2
Molecular Weight:
175.187
Pathway:
DNA Damage/DNA Repair; Apoptosis; Metabolism
Purity:
0.98
SMILES:
C=Cc1cncc2C(=O)OCCc12
Target:
TNF; transporter; PPAR

References

Kwak WJ, et al. Effects of gentianine on the production of pro-inflammatory cytokines in male Sprague-Dawley rats treated with lipopolysaccharide (LPS). Biol Pharm Bull. 2005;28(4):750-753. Wang N, et al. Machine learning enables discovery of Gentianine targeting TLR4/NF-?B pathway to repair ischemic stroke injury. Pharmacol Res. 2021;173:105913. Vaidya H, et al. Anti-diabetic activity of swertiamarin is due to an active metabolite, gentianine, that upregulates PPAR-? gene expression in 3T3-L1 cells. Phytother Res. 2013;27(4):624-627.