TargetMol

Liriodenine

Product Code:
 
TAR-TN1875
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1875-5mg5mg£504.00
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Quantity:
TAR-TN1875-1mL1 mL * 10 mM (in DMSO)£512.00
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Further Information

Bioactivity:
Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can suppress ventricular arrhythmias induced by myocardial ischaemia reperfusion, through inhibition of Na+ and the Ito channel. Liriodenine also has antimuscarinic properties, the antimuscarinic characteristics are similar to those of 4-diphenylacetoxy-N-methylpiperidine (4-DAMP, smooth muscle selective M3 antagonist), it may act as a selective M3 receptor antagonist in canine tracheal smooth muscle.
CAS:
475-75-2
Formula:
C17H9NO3
Molecular Weight:
275.263
Pathway:
Apoptosis; Proteases/Proteasome
Purity:
0.98
SMILES:
O=C1c2ccccc2-c2c3OCOc3cc3ccnc1c23
Target:
BCL; Caspase; p53

References

Liriodenine induces the apoptosis of human laryngocarcinoma cells via the upregulation of p53 expression.Oncol Lett. 2015 Mar;9(3):1121-1127.