TargetMol

Sophoflavescenol

Product Code:
 
TAR-TN2217
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN2217-5mg5mg£598.00
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Further Information

Bioactivity:
Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity without severe side effects. Sophoflavescenol exerts notable anti-inflammatory activity by inhibiting nitric oxide generation and tert-butylhydroperoxide-induced ROS generation rather than inhibiting nuclear factor kappa B activation in RAW 264.7 cells.
CAS:
216450-65-6
Formula:
C21H20O6
Molecular Weight:
368.385
Pathway:
Neuroscience; ; Metabolism
Purity:
0.9965
SMILES:
COc1cc(O)c(CC=C(C)C)c2oc(c(O)c(=O)c12)-c1ccc(O)cc1
Target:
Beta-Secretase; BACE; PDE; AChR; AChE

References

Anti-tumorigenic activity of sophoflavescenol against Lewis lung carcinoma in vitro and in vivo.Arch Pharm Res. 2011 Dec;34(12):2087-99.