TargetMol

Zedoarondiol

Product Code:
 
TAR-TN2327
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN2327-5mg5mg£568.00
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Quantity:
TAR-TN2327-1mL1 mL * 10 mM (in DMSO)£577.00
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Further Information

Bioactivity:
Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway.
CAS:
98644-24-7
Formula:
C15H24O3
Molecular Weight:
252.354
Pathway:
Neuroscience; NF-κb; Immunology/Inflammation
Purity:
0.98
SMILES:
CC(C)=C1C[C@H]2[C@@H](CC[C@@]2(C)O)[C@@](C)(O)CC1=O
Target:
NOS; NF-κB; COX

References

Zedoarondiol isolated from the rhizoma of Curcuma heyneana is involved in the inhibition of iNOS, COX-2 and pro-inflammatory cytokines via the downregulation of NF-kappaB pathway in LPS-stimulated murine macrophages.Int Immunopharmacol. 2009 Aug;9(9):1049-57.