TargetMol

Anatabine

Product Code:
 
TAR-TN3410
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN3410-5mg5mg£535.00
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Quantity:
TAR-TN3410-1mL1 mL * 10 mM (in DMSO)£631.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheimer's disease effects, it inhibits BACE-1 transcription and reduces BACE-1 protein levels in human neuronal like SHSY-5Y cells suggesting that the Aβ lowering properties of anatabine are mediated via a regulation of BACE-1 expression.
CAS:
581-49-7
Formula:
C10H12N2
Molecular Weight:
160.22
Pathway:
NF-κb; JAK/STAT signaling; Apoptosis; Neuroscience; Immunology/Inflammation; Stem Cells
Purity:
0.98
SMILES:
C1N[C@@H](CC=C1)c1cccnc1
Target:
Beta Amyloid; IL Receptor; TNF; NF-κB; BACE; COX; STAT