TargetMol

Boehmenan

Product Code:
 
TAR-TN3525
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TN3525-1mg1mg£292.00
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This product comes from: United States.
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Further Information

Bioactivity:
(?)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell lines, boehmenan-mediated anti-tumor property is mediated by modulation of mitochondria and EGFR signaling pathway in A549 NSCLC cells.
CAS:
57296-22-7
Formula:
C40H40O12
Molecular Weight:
712.8
Pathway:
Angiogenesis; MAPK; Metabolism; JAK/STAT signaling; Proteases/Proteasome; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors; DNA Damage/DNA Repair; Stem Cells
Purity:
0.98
SMILES:
COc1cc(CCCOC(=O)C=Cc2ccc(O)c(OC)c2)cc2[C@@H](COC(=O)C=Cc3ccc(O)c(OC)c3)[C@@H](Oc12)c1ccc(O)c(OC)c1
Target:
ERK; Phosphatase; EGFR; PARP; MEK; Wnt/beta-catenin; Akt; Caspase; STAT; p53