TargetMol

Dalbergioidin

Product Code:
 
TAR-TN3753
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TN3753-5mg5mg£440.00
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Quantity:
TAR-TN3753-1mL1 mL * 10 mM (in DMSO)£448.00
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Quantity:
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Further Information

Bioactivity:
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism. Dalbergioidin protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, suggests that it may be useful in bone metabolism diseases, particularly osteoporosis. Dalbergioidin also ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway.
CAS:
30368-42-4
Formula:
C15H12O6
Molecular Weight:
288.3
Pathway:
Immunology/Inflammation; Stem Cells; PI3K/Akt/mTOR signaling; Cytoskeletal Signaling; Proteases/Proteasome
Purity:
0.98
SMILES:
0
Target:
Tyrosinase; ROS; Akt; PI3K; TGF-beta/Smad