TargetMol

Elamipretide

Product Code:
 
TAR-TP1095
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP1095-1mg1mg£111.00
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TAR-TP1095-2mg2mg£129.00
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TAR-TP1095-5mg5mg£177.00
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TAR-TP1095-10mg10mg£242.00
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TAR-TP1095-25mg25mg£372.00
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TAR-TP1095-50mg50mg£522.00
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TAR-TP1095-100mg100mg£648.00
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TAR-TP1095-200mg200mg£870.00
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This product comes from: United States.
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Further Information

Bioactivity:
Elamipretide (SS-31,MTP-131,Bendavia) is a small mitochondrially-targeted tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that appears to reduce the production of toxic reactive oxygen species and stabilize cardiolipin.
CAS:
736992-21-5
Formula:
C32H49N9O5
Molecular Weight:
639.802
Purity:
0.9853
SMILES:
Cc1cc(O)cc(C)c1C[C@H](NC(=O)[C@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

References

Elamipretide. Yao S, Wu D, Hu X, et al.Platelet Membrane-Coated Bio-Nanoparticles of Indocyanine Green/Elamipretide for NIR Diagnosis and Antioxidant Therapy in Acute Kidney Injury.Acta Biomaterialia.2023 Suo M, Qi Y, Liu L, et al. SS31 Alleviates Pressure Overload-Induced Heart Failure Caused by Sirt3-Mediated Mitochondrial Fusion. Frontiers in Cardiovascular Medicine. 2022.9 Sabbah HN et al. Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure. Circ Heart Fail. 2016 Feb;9(2):e002206.