TargetMol

Porcine dynorphin A(1-13) acetate

Product Code:
 
TAR-TP1179L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP1179L-1mg1mg£125.00
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TAR-TP1179L-5mg5mg£185.00
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TAR-TP1179L-10mg10mg£253.00
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TAR-TP1179L-25mg25mg£439.00
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TAR-TP1179L-50mg50mg£611.00
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TAR-TP1179L-100mg100mg£840.00
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Further Information

Bioactivity:
Porcine dynorphin A(1-13) acetate is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.
CAS:
TP1179L
Formula:
C77H130N24O17
Molecular Weight:
1664
Pathway:
Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Purity:
0.9914
SMILES:
CC[C@H](C)[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)[C@H](CC3=CC=C(C=C3)O)N.CC(O)=O
Target:
Opioid Receptor

References

Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75.