TargetMol

Urotensin I acetate (83930-33-0 Free base)

Product Code:
 
TAR-TP1199L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TP1199L-1mg1mg£405.00
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TAR-TP1199L-5mg5mg£864.00
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TAR-TP1199L-10mg10mg£1,139.00
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TAR-TP1199L-25mg25mg£1,653.00
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Quantity:
TAR-TP1199L-50mg50mg£2,207.00
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Quantity:
TAR-TP1199L-100mg100mg£2,954.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Urotensin I acetate, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively[1][2].
CAS:
0
Formula:
0
Molecular Weight:
0
Pathway:
GPCR/G Protein
Purity:
0.9609
SMILES:
0
Target:
CRFR

References

Fryer J, et al. Urotensin I, a CRF-like neuropeptide, stimulates acth release from the teleost pituitary. Endocrinology. 1983;113(6):2308-2310. Reul JM, et al. Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr Opin Pharmacol. 2002 Feb;2(1):23-33. Smart D, et al. Characterisation using microphysiometry of CRF receptor pharmacology. Eur J Pharmacol. 1999 Aug 27;379(2-3):229-35. Gerritsen ME, et al. Urotensin I effects on intracellular content of cyclic AMP in the rat tail artery. Eur J Pharmacol. 1979;60(2-3):211-220.