TargetMol

Bacterial Sortase Substrate III, Abz/DNP

Product Code:
 
TAR-TP1634
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TP1634-1mg1mg£186.00
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Quantity:
TAR-TP1634-5mg5mg£417.00
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This product comes from: United States.
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Further Information

Bioactivity:
The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH2, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges.
CAS:
TP1634
Formula:
C41H57N11O14
Molecular Weight:
928
Purity:
0.98
SMILES:
0

References

Zhang J, et al. Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13517-22.