TargetMol

PUMA BH3

Product Code:
 
TAR-TP1724
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TP1724-1mg1mg£168.00
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TAR-TP1724-5mg5mg£302.00
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TAR-TP1724-10mg10mg£435.00
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Further Information

Bioactivity:
PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
CAS:
TP1724
Formula:
C128H202N42O43S
Molecular Weight:
3049.3
Purity:
0.98
SMILES:
0

References

Dai H, et al. Evaluation of the BH3-only protein Puma as a direct Bak activator. J Biol Chem. 2014 Jan 3;289(1):89-99.