TargetMol

HSDVHK-NH2

Product Code:
 
TAR-TP1879
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-TP1879-1mg1mg£128.00
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This product comes from: United States.
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Further Information

Bioactivity:
Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.
CAS:
848644-86-0
Formula:
C30H48N12O9
Molecular Weight:
720.78
Purity:
0.98
SMILES:
0

References

Choi et al (2010) Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin. Proteomics 10 72 PMID: Lee et al (2004) High-throughput screening of novel peptide inhibitors of an integrin receptor from the hexapeptide library by using a protein microarray chip. J.Biomol.Screen. 9 687 PMID: Bang et al (2011) Pharmacoproteomic analysis of a novel cell-permeable inhibitor of tumor-induced angiogenesis. Mol.Cell Proteomics 10 M110 PMID: