TargetMol

P11 acetate

Product Code:
 
TAR-TP1879L1
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TP1879L1-1mg1mg£136.00
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TAR-TP1879L1-5mg5mg£205.00
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TAR-TP1879L1-10mg10mg£298.00
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TAR-TP1879L1-25mg25mg£482.00
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TAR-TP1879L1-50mg50mg£667.00
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TAR-TP1879L1-100mg100mg£914.00
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Further Information

Bioactivity:
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).
CAS:
TP1879L1
Formula:
C30H48N12O9
Molecular Weight:
720.78
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
CC(C)[C@@H](C(N[C@@H](Cc1c[nH]cn1)C(N[C@@H](CCCCN)C(N)=O)=O)=O)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H](Cc1c[nH]cn1)N)=O)=O)=O
Target:
Integrin

References

Youngjin Choi, et al. Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin. Proteomics. 2010 Jan;10(1):72-80. Yoonsuk Lee, et al. High-throughput screening of novel peptide inhibitors of an integrin receptor from the hexapeptide library by using a protein microarray chip. J Biomol Screen. 2004 Dec;9(8):687-94. Ji-Young Bang, et al. Pharmacoproteomic analysis of a novel cell-permeable peptide inhibitor of tumor-induced angiogenesis. Mol Cell Proteomics. 2011 Aug;10(8):M110.005264.