TargetMol

Orphanin FQ(1-11)

Product Code:
 
TAR-TP1882
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP1882-1mg1mg£152.00
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Further Information

Bioactivity:
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.
CAS:
178249-41-7
Formula:
C49H75N15O14
Molecular Weight:
1098.2
Purity:
0.98
SMILES:
0

References

Rossi et al (1998) Orphanin FQ/nociceptin analgesia in the rat. Brain Res. 792 327 PMID: Rossi et al (1997) Pharmacological characterization of orphanin FQ/nociceptin and its fragments. J.Pharmacol.Exp.Ther. 282 858 PMID: Reinscheid et al (1996) Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J.Biol.Chem. 271 14163 PMID: