TargetMol

DynaMin inhibitory peptide, myristoylated

Product Code:
 
TAR-TP1907
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TP1907-1mg1mg£324.00
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Further Information

Bioactivity:
Cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization.
CAS:
251634-22-7
Formula:
C61H107N19O14
Molecular Weight:
1330.64
Purity:
0.98
SMILES:
0

References

Kittler et al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972 PMID: Nong et al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302 PMID: Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419 PMID: