TargetMol

CALP2

Product Code:
 
TAR-TP1909
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TP1909-1mg1mg£198.00
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Further Information

Bioactivity:
Cell-permeable calmodulin (CaM) antagonist that binds to the EF-hand/Ca2+-binding site. CALP2 has been demonstrated to inhibit CaM-dependant phosphodiesterase activity and increase intracellular Ca2+ concentrations by modulating Ca2+-channel activity. CALP2 has also been shown to be a potent activator of alveolar macrophages.
CAS:
261969-04-4
Formula:
C68H104N14O13S
Molecular Weight:
1357.72
Purity:
0.98
SMILES:
0

References

Ten Broeke et al (2004) Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages. Lab.Invest. 84 29 PMID: Houtman et al (2001) Attenuation of very late antigen-5-mediated adhesion of bone marrow-derived mast cells to fibronectin by peptides with inverted hydropathy to EF-hands. J.Immunol. 166 861 PMID: Ten Broeke et al (2001) Calcium sensors as new therapeutic targets for airway hyperresponsiveness and asthma. FASEB J. 15 1831 PMID: