TargetMol

tcY-NH2 TFA(327177-34-4 free base)

Product Code:
 
TAR-TP1925L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-TP1925L-1mg1mg£213.00
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TAR-TP1925L-5mg5mg£390.00
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TAR-TP1925L-10mg10mg£551.00
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TAR-TP1925L-25mg25mg£838.00
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TAR-TP1925L-50mg50mg£1,107.00
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Quantity:
TAR-TP1925L-100mg100mg£1,460.00
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Quantity:
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Further Information

Bioactivity:
tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.
CAS:
TP1925L
Formula:
C42H50F3N7O9
Molecular Weight:
853.9
Pathway:
GPCR/G Protein
Purity:
1
SMILES:
C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)/C=C/C3=CC=CC=C3)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N.O=C(O)C(F)(F)F
Target:
Protease-activated Receptor

References

Ma et al (2001) Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist. Br.J.Pharmacol. 134 701 PMID: Hollenberg and Saifeddine (2001) Proteinase-activated receptor 4 (PAR4): activation and inhibition of rat platelet aggregation by PAR4-derived peptides. Can.J.Physiol.Pharmacol. 79 439 PMID: Hollenberg et al (2004) Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo. Br.J.Pharmacol. 143 443 PMID: