TargetMol

RFRP-3(human)

Product Code:
 
TAR-TP1936
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-TP1936-1mg1mg£164.00
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TAR-TP1936-5mg5mg£393.00
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TAR-TP1936-10mg10mg£576.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons.
CAS:
311309-27-0
Formula:
C45H72N14O10
Molecular Weight:
969.15
Purity:
0.98
SMILES:
0

References

Ubuka et al (2009) Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis. PLoS One 4 e8400 PMID: Hinuma et al (2000) New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat.Cell Biol. 2 703 PMID: Rizwan et al (2012) RFamide-related peptide-3 receptor gene expression in GnRH and kisspeptin neurons and GnRH-dependent mechanism of action. Endocrinology 153 3770 PMID: