TargetMol

RFRP3(human) acetate(311309-27-0 free base)

Product Code:
 
TAR-TP1936L1
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP1936L1-1mg1mg£177.00
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TAR-TP1936L1-5mg5mg£313.00
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TAR-TP1936L1-10mg10mg£434.00
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TAR-TP1936L1-25mg25mg£670.00
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TAR-TP1936L1-50mg50mg£914.00
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Quantity:
TAR-TP1936L1-100mg100mg£1,211.00
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Further Information

Bioactivity:
RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM.
CAS:
TP1936L1
Formula:
C47H76N14O12
Molecular Weight:
1029.19
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9709
SMILES:
CC(C)C[C@@]([H])(C(N1CCC[C@]1(/C(O)=N/[C@@]([H])(CCC(O)=N)/C(O)=N/[C@@]([H])(CCCNC(N)=N)/C(O)=N/[C@@]([H])(CC2=CC=CC=C2)C(O)=N)[H])=O)/N=C([C@]([H])(CC(O)=N)/N=C([C@@]3(CCCN3C([C@]([H])(C(C)C)N)=O)[H])O)O.CC(O)=O
Target:
Neuropeptide Y Receptor

References

IJ Clarke, IP Sari, Y Qi,etc. Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion.[J]. Endocrinology, 2008(11):5811.