TargetMol

RS09 2TFA (1449566-36-2 free base)

Product Code:
 
TAR-TP1938L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP1938L-1mg1mg£181.00
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TAR-TP1938L-5mg5mg£317.00
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TAR-TP1938L-10mg10mg£440.00
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TAR-TP1938L-25mg25mg£679.00
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TAR-TP1938L-50mg50mg£922.00
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Quantity:
TAR-TP1938L-100mg100mg£1,219.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
RS09 2TFA is a TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. It acts as an adjuvant in vivo and enhances X-15 specific antibody serum concentrations.
CAS:
TP1938L
Formula:
C35H51F6N9O13
Molecular Weight:
919.82
Pathway:
Immunology/Inflammation
Purity:
1
SMILES:
O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.OC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC1=CNC=N1)NC([C@H]2N(C([C@H]3N(C([C@H](C)N)=O)CCC3)=O)CCC2)=O)=O)=O)=O
Target:
TLR

References

Shanmugam et al (2012) Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. PLoS One 7 e30839 PMID: Li et al (2016) Intranasal vaccination against HIV-1 with adenoviral vector-based nanocomplex using synthetic TLR-4 agonist peptide as adjuvant. Mol.Pharm. 13 885 PMID: