TargetMol

(D)-PPA 1

Product Code:
 
TAR-TP1960
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TP1960-1mg1mg£238.00
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Further Information

Bioactivity:
PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.
CAS:
1620813-53-7
Formula:
C70H98N20O21
Molecular Weight:
1555.67
Purity:
0.98
SMILES:
0

References

Chang et al (2015) Blocking of the PD-1/PD-L1 interaction by a D-peptide antagonist for cancer immunotherapy. Angew Chem.Int.Ed.Engl. 54 11760 PMID: