TargetMol

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide

Product Code:
 
TAR-TP1963
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TP1963-1mg1mg£350.00
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Further Information

Bioactivity:
Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.
CAS:
313988-89-5
Formula:
C183H281N57O54S2
Molecular Weight:
4207.67
Purity:
0.98
SMILES:
0

References

Cabrele et al (2000) The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats. J.Biol.Chem. 275 36043 PMID: Dumont et al (2005) BODIPY?-conjugated neuropeptide Y ligands: new fluorescent tools to tag Y1, Y2, Y4 and Y5 receptor subtypes. Br.J.Pharmacol. 146 1069 PMID: