TargetMol

YAP-TEAD-IN-1 TFA

Product Code:
 
TAR-TP2160L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP2160L-1mg1mg£191.00
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TAR-TP2160L-5mg5mg£347.00
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TAR-TP2160L-10mg10mg£529.00
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This product comes from: United States.
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Further Information

Bioactivity:
YAP-TEAD-IN-1 TFA is a competitive inhibitor of YAP?TEAD interaction (IC50: 25 nM). It shows a higher binding affinity to TEAD1 (Kd: 15 nM) than YAP (50-171) (Kd: 40 nM).
CAS:
1659305-79-9
Formula:
C93H144ClN23O21S2.xC2HF3O2
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Zhang Z, et al. Structure-Based Design and Synthesis of Potent Cyclic Peptides Inhibiting the YAP-TEAD Protein-Protein Interaction.ACS Med Chem Lett. 2014 Jul 14;5(9):993-8.