TargetMol

Senecionine

Product Code:
 
TAR-TQ0192
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0192-1mg1mg£138.00
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TAR-TQ0192-5mg5mg£228.00
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TAR-TQ0192-1mL1 mL * 10 mM (in DMSO)£239.00
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TAR-TQ0192-10mg10mg£307.00
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TAR-TQ0192-25mg25mg£470.00
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TAR-TQ0192-50mg50mg£651.00
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TAR-TQ0192-100mg100mg£863.00
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Further Information

Bioactivity:
Senecionine is the hepatotoxic pyrrolizidine alkaloids isolated from Senecio vulgaris.
CAS:
130-01-8
Formula:
C18H25NO5
Molecular Weight:
335.4
Purity:
0.978
SMILES:
CC=C1C[C@@H](C)[C@@](C)(O)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@@H]23

References

D S Griffin, et al. Effects of the Pyrrolizidine Alkaloid Senecionine and the Alkenals trans-4-OH-hexenal and trans-2-hexenal on Intracellular Calcium Compartmentation in Isolated Hepatocytes. Biochem Pharmacol. 1989 Feb 1; 38 (3), 391-7 Wang C, et al. The comparative pharmacokinetics of two pyrrolizidine alkaloids, senecionine and adonifoline, and their main metabolites in rats after intravenous and oral administration by UPLC/ESIMS. Anal Bioanal Chem. 2011 Jul;401(1):275-87. Tu ZB, et al. Identification of senecionine and senecionine N-oxide as antifertility constituents in Senecio vulgaris. J Pharm Sci. 1988 May;77(5):461-3. Kakrani HK, et al. Effect of seneciphylline and senecionine on hepatic drug metabolizing enzymes in rats. J Ethnopharmacol. 1984 Dec;12(3):271-8.