TargetMol

Procyanidin B1

Product Code:
 
TAR-TQ0205
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-TQ0205-1mg1mg£108.00
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TAR-TQ0205-5mg5mg£213.00
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TAR-TQ0205-1mL1 mL * 10 mM (in DMSO)£258.00
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TAR-TQ0205-10mg10mg£303.00
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TAR-TQ0205-25mg25mg£463.00
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TAR-TQ0205-50mg50mg£621.00
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TAR-TQ0205-100mg100mg£849.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Procyanidin B1, isolated from commonly eaten fruits, binds to the TLR4/MD-2 complex and has anti-inflammatory activity.
CAS:
20315-25-7
Formula:
C30H26O12
Molecular Weight:
578.526
Pathway:
Immunology/Inflammation
Purity:
0.9913
SMILES:
O[C@H]1Cc2c(O)cc(O)c([C@@H]3[C@@H](O)[C@H](Oc4cc(O)cc(O)c34)c3ccc(O)c(O)c3)c2O[C@@H]1c1ccc(O)c(O)c1
Target:
TLR

References

Kanno H, et al. Protective effects of glycycoumarin and procyanidin B1, active components of traditional Japanese medicine yokukansan, on amyloid ? oligomer-induced neuronal death. J Ethnopharmacol. 2015 Jan 15;159:122-8. Shimada T, et al. Flavangenol (pine bark extract) and its major component procyanidin B1 enhance fatty acid oxidation in fat-loaded models. Eur J Pharmacol. 2012 Feb 29;677(1-3):147-53. Xing J, et al. Anti-inflammatory effect of procyanidin B1 on LPS-treated THP1 cells via interaction with the TLR4-MD-2 heterodimer and p38 MAPK and NF-?B signaling. Mol Cell Biochem. 2015 Sep;407(1-2):89-95.