TargetMol

Deoxyandrographolide

Product Code:
 
TAR-TQ0218
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-TQ0218-1mg1mg£222.00
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TAR-TQ0218-5mg5mg£389.00
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TAR-TQ0218-1mL1 mL * 10 mM (in DMSO)£430.00
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TAR-TQ0218-10mg10mg£530.00
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TAR-TQ0218-25mg25mg£780.00
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TAR-TQ0218-50mg50mg£1,026.00
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This product comes from: United States.
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Further Information

Bioactivity:
Deoxyandrographolide potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6.
CAS:
79233-15-1
Formula:
C20H30O4
Molecular Weight:
334.456
Pathway:
Apoptosis; Immunology/Inflammation
Purity:
0.98
SMILES:
CC1=C(CCC2=CCOC2=O)[C@]2(C)CC[C@@H](O)[C@@](C)(CO)[C@H]2CC1
Target:
IL Receptor; TNF

References

Deng S, et al. Microbial transformation of deoxyandrographolide and their inhibitory activity on LPS-induced NO production in RAW 264.7 macrophages. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1615-8. Arha D, et al. Deoxyandrographolide promotes glucose uptake through glucose transporter-4 translocation to plasma membrane in L6 myotubes and exerts antihyperglycemic effect in vivo. Eur J Pharmacol. 2015 Dec 5;768:207-16. Xu Y, et al. Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. Bioorg Med Chem. 2019;27(11):2209-2219. Xin XL, et al. Microbial transformation of deoxyandrographolide by Fusarium graminearum AS 3.4598. J Asian Nat Prod Res. 2011 Apr;13(4):350-5.