TargetMol

Glaucocalyxin B

Product Code:
 
TAR-TQ0309
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TQ0309-1mg1mg£204.00
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TAR-TQ0309-5mg5mg£364.00
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Further Information

Bioactivity:
Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).
CAS:
80508-81-2
Formula:
C22H30O5
Molecular Weight:
374.477
Pathway:
Autophagy
Purity:
0.9913
SMILES:
[H][C@@]12CCC3[C@@H](OC(C)=O)[C@@]1(C(O)C[C@]1([H])C(C)(C)C(=O)CC[C@@]21C)C(=O)C3=C
Target:
Autophagy

References

Yang WH, et al. Glaucocalyxin A and B-induced cell death is related to GSH perturbation in human leukemia HL-60 cells. Anticancer Agents Med Chem. 2013 Oct;13(8):1280-90. Pan Y, et al. Glaucocalyxin B induces apoptosis and autophagy in human cervical cancer cells. Mol Med Rep. 2016 Aug;14(2):1751-5. Gan P, et al. Anti-inflammatory effects of glaucocalyxin B in microglia cells. J Pharmacol Sci. 2015 May;128(1):35-46.