TargetMol

(Rac)-IBT6A

Product Code:
 
TAR-T10626
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10626-1mg1mg£136.00
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TAR-T10626-2mg2mg£164.00
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TAR-T10626-5mg5mg£214.00
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TAR-T10626-1mL1 mL * 10 mM (in DMSO)£226.00
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TAR-T10626-10mg10mg£280.00
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TAR-T10626-25mg25mg£421.00
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TAR-T10626-50mg50mg£587.00
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TAR-T10626-100mg100mg£807.00
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TAR-T10626-500mg500mg£1,564.00
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Further Information

Bioactivity:
(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.
CAS:
1412418-47-3
Formula:
C22H22N6O
Molecular Weight:
386.459
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis;
Purity:
0.9868
SMILES:
Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCNC1
Target:
BTK

References

1. Somana Siva Prasad, et al. A QUALITY BY DESIGN APPROACH FOR DEVELOPMENT OF SIMPLE AND ROBUST REVERSED PHASE STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF IBRUTINIB AND ITS IMPURITIES. 2. Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80. 3. Liu N, et al. Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study. Org Biomol Chem. 2015 May 14;13(18):5147-57.