TargetMol

Emixustat hydrochloride

Product Code:
 
TAR-T11188L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11188L-1mg1mg£125.00
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TAR-T11188L-2mg2mg£149.00
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TAR-T11188L-1mL1 mL * 10 mM (in DMSO)£201.00
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TAR-T11188L-5mg5mg£214.00
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TAR-T11188L-10mg10mg£299.00
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TAR-T11188L-25mg25mg£454.00
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TAR-T11188L-50mg50mg£622.00
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TAR-T11188L-100mg100mg£872.00
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This product comes from: United States.
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Further Information

Bioactivity:
Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ? 3 nM. 11-cis-retinol Emixustat hydrochloride is a novel visual cycle modulator.
CAS:
1141934-97-5
Formula:
C16H26ClNO2
Molecular Weight:
299.84
Purity:
0.9948
SMILES:
Cl.NCC[C@@H](O)c1cccc(OCC2CCCCC2)c1

References

1. Kiser PD, et al. Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nat Chem Biol. 2015 Jun;11(6):409-15. 2. Kubota R, et al. Phase 1, dose-ranging study of emixustat hydrochloride (ACU-4429), a novel visual cycle modulator, in healthy volunteers. Retina. 2014 Mar;34(3):603-9.