TargetMol

FIDAS-3

Product Code:
 
TAR-T11284
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11284-1mg1mg£115.00
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TAR-T11284-1mL1 mL * 10 mM (in DMSO)£166.00
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TAR-T11284-5mg5mg£168.00
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TAR-T11284-10mg10mg£229.00
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TAR-T11284-25mg25mg£374.00
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TAR-T11284-50mg50mg£527.00
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Quantity:
TAR-T11284-100mg100mg£725.00
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Quantity:
TAR-T11284-500mg500mg£1,420.00
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Further Information

Bioactivity:
FIDAS-3 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-3 has anticancer activities. FIDAS-3 is a stilbene derivative and is a potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A).
CAS:
1266684-01-8
Formula:
C16H15F2N
Molecular Weight:
259.3
Pathway:
Cytoskeletal Signaling; ; Stem Cells
Purity:
0.9859
SMILES:
CN(C)c1ccc(C=Cc2c(F)cccc2F)cc1
Target:
Wnt/beta-catenin

References

1. Zhang W, et al. Fluorinated N,N-dialkylaminostilbenes repress colon cancer by targeting methionine S-adenosyltransferase 2A. ACS Chem Biol. 2013 Apr 19;8(4):796-803. 2. Zhang W, et al. Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression. J Med Chem. 2011 Mar 10;54(5):1288-97.