TargetMol

nor-NOHA acetate

Product Code:
 
TAR-T12240
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T12240-10mg10mg£337.00
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Further Information

Bioactivity:
nor-NOHA acetate is a reversible inhibitor of arginase, with anti-leukemic activity, effective in endothelial dysfunction, immunosuppression, and metabolism.
CAS:
1140844-63-8
Formula:
C9H20N4O7
Molecular Weight:
296.28
Pathway:
Immunology/Inflammation; Apoptosis
Purity:
0.98
SMILES:
CC(O)=O.CC(O)=O.N[C@@H](CCNC(=N)NO)C(O)=O
Target:
Apoptosis; Arginase

References

1. Ng KP, et al. The arginase inhibitor N?-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target. PLoS One. 2018 Oct 11;13(10):e0205254.