TargetMol

ORM-15341

Product Code:
 
TAR-T12323
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12323-1mg1mg£95.00
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TAR-T12323-5mg5mg£128.00
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TAR-T12323-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T12323-10mg10mg£168.00
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TAR-T12323-25mg25mg£230.00
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TAR-T12323-50mg50mg£365.00
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TAR-T12323-100mg100mg£511.00
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This product comes from: United States.
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Further Information

Bioactivity:
ORM-15341 is a potent and full antagonist for human AR (hAR)( with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells)
CAS:
1297537-33-7
Formula:
C19H17ClN6O2
Molecular Weight:
396.84
Pathway:
Endocrinology/Hormones
Purity:
0.9861
SMILES:
C[C@@H](Cn1ccc(n1)-c1ccc(C#N)c(Cl)c1)NC(=O)c1cc([nH]n1)C(C)=O
Target:
Androgen Receptor

References

1. Moilanen AM, et al. Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms toandrogen signaling-directed prostate cancer therapies. Sci Rep. 2015 Jul 3;5:12007. doi: 10.1038/srep12007. 2. Toermaekangas Olli, et al. Preparation of heteroaryl carboxamides as androgen receptor modulators. From PCT Int. Appl. (2012), WO 2012143599 A1 20121026.