TargetMol

Pifithrin- α, p-Nitro, Cyclic

Product Code:
 
TAR-T12472
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12472-1mg1mg£98.00
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TAR-T12472-2mg2mg£109.00
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TAR-T12472-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T12472-5mg5mg£135.00
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TAR-T12472-10mg10mg£173.00
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TAR-T12472-25mg25mg£282.00
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TAR-T12472-50mg50mg£414.00
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TAR-T12472-100mg100mg£584.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form inhibitor of p53.
CAS:
60477-38-5
Formula:
C15H13N3O2S
Molecular Weight:
299.35
Pathway:
Apoptosis
Purity:
0.9997
SMILES:
[O-][N+](=O)c1ccc(cc1)-c1cn2c3CCCCc3sc2n1
Target:
p53

References

1. Pietrancosta N, et al. Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism. J Med Chem. 2006 Jun 15;49(12):3645-52. 2. Dinca EB, et al. p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts. Cancer Res. 2008 Dec 15;68(24):10034-9.