TargetMol

S55746

Product Code:
 
TAR-T12824L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T12824L-1mg1mg£111.00
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TAR-T12824L-2mg2mg£130.00
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TAR-T12824L-5mg5mg£159.00
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TAR-T12824L-1mL1 mL * 10 mM (in DMSO)£177.00
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TAR-T12824L-10mg10mg£231.00
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TAR-T12824L-25mg25mg£362.00
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TAR-T12824L-50mg50mg£535.00
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TAR-T12824L-100mg100mg£740.00
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This product comes from: United States.
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Further Information

Bioactivity:
S55746 is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM).
CAS:
1448584-12-0
Formula:
C43H42N4O6
Molecular Weight:
710.831
Pathway:
Apoptosis
Purity:
0.9899
SMILES:
Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1
Target:
BCL

References

1. Casara P, et al. S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth. Oncotarget. 2018 Apr 13;9(28):20075-20088.