TargetMol

SR59230A

Product Code:
 
TAR-T13016
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13016-1mg1mg£109.00
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TAR-T13016-2mg2mg£127.00
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TAR-T13016-5mg5mg£158.00
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TAR-T13016-1mL1 mL * 10 mM (in DMSO)£173.00
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TAR-T13016-10mg10mg£217.00
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TAR-T13016-25mg25mg£360.00
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TAR-T13016-50mg50mg£502.00
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TAR-T13016-100mg100mg£693.00
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Further Information

Bioactivity:
SR59230A is a potent, selective antagonist of β3-adrenergic receptor(β3, β1, and β2 receptors with IC50s of 40, 408, and 648 nM , respectively).
CAS:
174689-39-5
Formula:
C23H29NO6
Molecular Weight:
415.486
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9946
SMILES:
OC(=O)C(O)=O.CCc1ccccc1OC[C@@H](O)CN[C@H]1CCCc2ccccc12
Target:
Adrenergic Receptor

References

1. Bruno G, et al. ?3-adrenoreceptor blockade reduces tumor growth and increases neuronal differentiation in neuroblastoma via SK2/S1P2 modulation.Oncogene. 2020 Jan;39(2):368-384. 2. Nisoli E, et al. Functional studies of the first selective beta 3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes.Mol Pharmacol. 1996 Jan;49(1):7-14.