TargetMol

VAF347

Product Code:
 
TAR-T13276
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13276-1mg1mg£98.00
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TAR-T13276-2mg2mg£108.00
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TAR-T13276-5mg5mg£132.00
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TAR-T13276-1mL1 mL * 10 mM (in DMSO)£163.00
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TAR-T13276-10mg10mg£168.00
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TAR-T13276-25mg25mg£249.00
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TAR-T13276-50mg50mg£369.00
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TAR-T13276-100mg100mg£517.00
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Quantity:
TAR-T13276-500mg500mg£1,050.00
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Further Information

Bioactivity:
VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects.
CAS:
574759-62-9
Formula:
C17H11ClF3N3
Molecular Weight:
349.74
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
FC(F)(F)c1ccc(Nc2nccc(n2)-c2cccc(Cl)c2)cc1
Target:
Aryl Hydrocarbon Receptor

References

1. Ibabao CN, et al. The AhR agonist VAF347 augments retinoic acid-induced differentiation in leukemia cells. FEBS Open Bio. 2015 Apr 8;5:308-18. 2. B Paige Lawrence, et al. Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound. Blood. 2008 Aug 15;112(4):1158-65.