TargetMol

VU 0365114

Product Code:
 
TAR-T13325
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13325-1mg1mg£101.00
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TAR-T13325-2mg2mg£114.00
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TAR-T13325-5mg5mg£142.00
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TAR-T13325-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T13325-10mg10mg£171.00
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TAR-T13325-25mg25mg£257.00
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TAR-T13325-50mg50mg£385.00
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TAR-T13325-100mg100mg£544.00
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TAR-T13325-500mg500mg£1,099.00
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This product comes from: United States.
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Further Information

Bioactivity:
VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).
CAS:
1208222-39-2
Formula:
C22H14F3NO3
Molecular Weight:
397.353
Pathway:
Neuroscience
Purity:
0.98
SMILES:
FC(F)(F)Oc1ccc2N(Cc3ccc(cc3)-c3ccccc3)C(=O)C(=O)c2c1
Target:
AChR

References

1. Bridges TM, et al. Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5617-22.