TargetMol

(R)-ADX-47273

Product Code:
 
TAR-T13441
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13441-1mg1mg£109.00
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TAR-T13441-2mg2mg£125.00
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TAR-T13441-5mg5mg£161.00
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TAR-T13441-1mL1 mL * 10 mM (in DMSO)£171.00
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TAR-T13441-10mg10mg£229.00
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TAR-T13441-25mg25mg£358.00
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TAR-T13441-50mg50mg£542.00
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TAR-T13441-100mg100mg£744.00
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TAR-T13441-500mg500mg£1,428.00
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Further Information

Bioactivity:
(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).
CAS:
851881-59-9
Formula:
C20H17F2N3O2
Molecular Weight:
369.372
Pathway:
Neuroscience
Purity:
0.98
SMILES:
Fc1ccc(cc1)C(=O)N1CCC[C@H](C1)c1nc(no1)-c1ccc(F)cc1
Target:
GluR

References

1. Engers DW, et al. Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-4727ChemMedChem. 2009 Apr;4(4):505-11.