TargetMol

Dorzagliatin

Product Code:
 
TAR-T15159
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15159-1mg1mg£98.00
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TAR-T15159-2mg2mg£109.00
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TAR-T15159-5mg5mg£134.00
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TAR-T15159-1mL1 mL * 10 mM (in DMSO)£140.00
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TAR-T15159-10mg10mg£171.00
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TAR-T15159-25mg25mg£274.00
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TAR-T15159-50mg50mg£389.00
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TAR-T15159-100mg100mg£550.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Dorzagliatin is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
CAS:
1191995-00-2
Formula:
C22H27ClN4O5
Molecular Weight:
462.93
Pathway:
Metabolism
Purity:
0.9974
SMILES:
CC(C)C[C@H](N1CC(Oc2ccccc2Cl)=CC1=O)C(=O)Nc1ccn(C[C@@H](O)CO)n1
Target:
Glucokinase

References

1. Zhu XX, et al. Dorzagliatin (HMS5552), a novel dual-acting glucokinase activator, improves glycaemic control and pancreatic ?-cell function in patients with type 2 diabetes: A 28-day treatment study using biomarker-guided patient selection. Diabetes Obes Metab. 2018 Sep;20(9):2113-2120. 2. Wang P, et al. Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus. J Diabetes Res. 2017;2017:5812607.