TargetMol

ESI-05

Product Code:
 
TAR-T15247
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15247-2mg2mg£97.00
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TAR-T15247-5mg5mg£112.00
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TAR-T15247-1mL1 mL * 10 mM (in DMSO)£117.00
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TAR-T15247-10mg10mg£146.00
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TAR-T15247-25mg25mg£206.00
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TAR-T15247-50mg50mg£299.00
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Quantity:
TAR-T15247-100mg100mg£462.00
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Further Information

Bioactivity:
ESI-05 is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
CAS:
5184-64-5
Formula:
C16H18O2S
Molecular Weight:
274.38
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
Cc1ccc(cc1)S(=O)(=O)c1c(C)cc(C)cc1C
Target:
cAMP

References

1. Tsalkova T, et al. Isoform-specific antagonists of exchange proteins directly activated by cAMP. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18613-8.