TargetMol

P-1075

Product Code:
 
TAR-T16420
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16420-1mg1mg£115.00
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TAR-T16420-2mg2mg£135.00
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TAR-T16420-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T16420-5mg5mg£173.00
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TAR-T16420-10mg10mg£242.00
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TAR-T16420-25mg25mg£386.00
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TAR-T16420-50mg50mg£544.00
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TAR-T16420-100mg100mg£748.00
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Quantity:
TAR-T16420-500mg500mg£1,460.00
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Further Information

Bioactivity:
P-1075 is a potent sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6) activator (EC50 = 45 nM). P-1075 opens opens mitoKATP channels and may be cardioprotective.
CAS:
60559-98-0
Formula:
C12H17N5
Molecular Weight:
231.303
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
CCC(C)(C)NC(NC#N)=Nc1cccnc1
Target:
Potassium Channel

References

1. Schwanstecher M, et al. Potassium channel openers require ATP to bind to and act through sulfonylurea receptors. EMBO J. 1998 Oct 1;17(19):5529-35. 2. Oldenburg O, et al. P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts. J Mol Cell Cardiol. 2003 Sep;35(9):1035-42.