TargetMol

ROC-325

Product Code:
 
TAR-T16777
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16777-1mg1mg£109.00
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TAR-T16777-2mg2mg£125.00
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TAR-T16777-5mg5mg£148.00
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TAR-T16777-1mL1 mL * 10 mM (in DMSO)£166.00
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TAR-T16777-10mg10mg£205.00
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TAR-T16777-25mg25mg£341.00
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TAR-T16777-50mg50mg£510.00
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TAR-T16777-100mg100mg£704.00
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TAR-T16777-500mg500mg£1,380.00
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Further Information

Bioactivity:
ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity.
CAS:
1859141-26-6
Formula:
C28H27ClN4OS
Molecular Weight:
503.06
Pathway:
Autophagy; Apoptosis
Purity:
0.9926
SMILES:
CN(CCNc1ccnc2cc(Cl)ccc12)CCNc1ccc(C)c2sc3ccccc3c(=O)c12
Target:
Apoptosis; Autophagy

References

1. Carew JS, et al. Disruption of Autophagic Degradation with ROC-325 Antagonizes Renal Cell Carcinoma Pathogenesis. Clin Cancer Res. 2017 Jun 1;23(11):2869-2879.