TargetMol

RS 17053 hydrochloride

Product Code:
 
TAR-T16798
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T16798-50mg50mgEnquire
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TAR-T16798-2mg2mg£98.00
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TAR-T16798-5mg5mg£115.00
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TAR-T16798-1mL1 mL * 10 mM (in DMSO)£123.00
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Further Information

Bioactivity:
RS 17053 hydrochloride is an effective and selective antagonist of α1A-adrenergic receptor with pA2 of 9.8 in functional assays and pKi of 9.1 in the native cell membrane.
CAS:
169505-93-5
Formula:
C24H30Cl2N2O2
Molecular Weight:
449.42
Pathway:
Neuroscience; ; GPCR/G Protein
Purity:
0.98
SMILES:
Cl.CC(C)(Cc1c[nH]c2ccc(Cl)cc12)NCCOc1ccccc1OCC1CC1
Target:
Adrenergic Receptor

References

1. Ford AP, et al. RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification. Mol Pharmacol. 1996 Feb;49(2):209-15. 2. Wellman PJ, et al. Effects of the alpha 1a-adrenoceptor antagonist RS-17053 on phenylpropanolamine-induced anorexia in rats. Pharmacol Biochem Behav. 1997 May-Jun;57(1-2):281-4.