TargetMol

Smurf1-IN-A01

Product Code:
 
TAR-T16904
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16904-1mg1mg£96.00
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TAR-T16904-2mg2mg£107.00
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TAR-T16904-5mg5mg£128.00
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TAR-T16904-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T16904-10mg10mg£168.00
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TAR-T16904-25mg25mg£269.00
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TAR-T16904-50mg50mg£389.00
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TAR-T16904-100mg100mg£544.00
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This product comes from: United States.
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Further Information

Bioactivity:
Smurf1-IN-A01 is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.
CAS:
1007647-73-5
Formula:
C22H20ClF3N4O3S
Molecular Weight:
512.93
Purity:
0.9954
SMILES:
Cc1ccnn1-c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F

References

1. Cao Y, et al. Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation. Sci Rep. 2014 May 14;4:4965.