TargetMol

TAO Kinase inhibitor 1

Product Code:
 
TAR-T16987
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16987-5mg5mg£122.00
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TAR-T16987-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T16987-10mg10mg£148.00
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TAR-T16987-25mg25mg£241.00
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TAR-T16987-50mg50mg£389.00
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TAR-T16987-100mg100mg£546.00
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Quantity:
TAR-T16987-500mg500mg£1,099.00
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This product comes from: United States.
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Further Information

Bioactivity:
TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectively).
CAS:
850467-66-2
Formula:
C25H24N2O2
Molecular Weight:
384.479
Pathway:
; MAPK
Purity:
0.9945
SMILES:
O=C(CNC(=O)c1ccc(cc1)-c1ccccc1)NC1CCCc2ccccc12
Target:
MAPK

References

1. Koo CY, et al. Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells. Mol Cancer Ther. 2017 Nov;16(11):2410-2421.