TargetMol

TVB-3166

Product Code:
 
TAR-T17180
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17180-1mg1mg£98.00
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TAR-T17180-2mg2mg£109.00
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TAR-T17180-5mg5mg£135.00
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TAR-T17180-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T17180-10mg10mg£165.00
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TAR-T17180-25mg25mg£245.00
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TAR-T17180-50mg50mg£369.00
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TAR-T17180-100mg100mg£517.00
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Further Information

Bioactivity:
TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective fatty acid synthase inhibitor (IC50s: 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively).
CAS:
1533438-83-3
Formula:
C24H24N4O
Molecular Weight:
384.483
Pathway:
; Metabolism; Apoptosis
Purity:
0.9953
SMILES:
CC1=CC(C)=C(C(=O)N2CC(C3=CC=C(C#N)C=C3)C2)C=C1C1=NNC(C)=C1C
Target:
Apoptosis; Fatty Acid Synthase

References

1. Ventura R, et al. Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression. EBioMedicine. 2015 Jul 2;2(8):808-24.