TargetMol

VAL-083

Product Code:
 
TAR-T17212
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17212-1mg1mg£135.00
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TAR-T17212-2mg2mg£166.00
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TAR-T17212-1mL1 mL * 10 mM (in DMSO)£196.00
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TAR-T17212-5mg5mg£217.00
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TAR-T17212-10mg10mg£269.00
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TAR-T17212-25mg25mg£404.00
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TAR-T17212-50mg50mg£566.00
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TAR-T17212-100mg100mg£776.00
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Further Information

Bioactivity:
VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
CAS:
23261-20-3
Formula:
C6H10O4
Molecular Weight:
146.142
Pathway:
DNA Damage/DNA Repair
Purity:
0.98
SMILES:
[H][C@@]1(CO1)[C@H](O)[C@H](O)[C@]1([H])CO1
Target:
DNA Alkylator/Crosslinker; DNA Alkylation

References

1. Kaiji Hu, et al. Abstract 811: VAL083, a novel N7 alkylating agent, surpasses NSC 362856 activity and inhibits cancer stem cells providing a new potential treatment option for glioblastoma multiforme. Cancer Research. 2012 Mar 31-Apr 4. 2. Jiang X, et al. Dianhydrogalactitol, a potential multitarget agent, inhibits glioblastoma migration, invasion, and angiogenesis. Biomed Pharmacother. 2017 Jul;91:1065-1074. 3. Peng C, et al. 1,2:5,6-dianhydrogalactitol inhibits human glioma cell growth in vivo and in vitro by arresting the cell cycle at G2/M phase. Acta Pharmacol Sin. 2017 Apr;38(4):561-570.