TargetMol

(Z)-Guggulsterone

Product Code:
 
TAR-T17280
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17280-5mg5mg£144.00
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TAR-T17280-1mL1 mL * 10 mM (in DMSO)£151.00
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TAR-T17280-10mg10mg£176.00
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TAR-T17280-25mg25mg£280.00
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TAR-T17280-50mg50mg£385.00
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TAR-T17280-100mg100mg£542.00
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Further Information

Bioactivity:
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF?VEGF-R2?Akt signaling axis.
CAS:
39025-23-5
Formula:
C21H28O2
Molecular Weight:
312.453
Pathway:
Cytoskeletal Signaling; Tyrosine Kinase/Adaptors; Angiogenesis; Apoptosis; PI3K/Akt/mTOR signaling
Purity:
0.9972
SMILES:
CC=C1/C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Target:
Apoptosis; VEGFR; Akt

References

1. Xiao D, et al. z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo. Mol Cancer Ther. 2008 Jan;7(1):171-80.